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Rethinking risk for pneumococcal disease in adults: the role of risk stacking.


ABSTRACT: Using data from 3 private healthcare claims repositories, we evaluated the incidence of pneumococcal disease among adults with US Advisory Committee on Immunization Practices (ACIP) defined at-risk conditions or rheumatoid arthritis, lupus, Crohn's disease, and neuromuscular disorder/seizures and those with traditional high-risk conditions. We observed that adults with ?2 concurrent comorbid conditions had pneumococcal disease incidence rates that were as high as or higher than rates observed in those with traditional high-risk conditions.

SUBMITTER: Pelton SI 

PROVIDER: S-EPMC4438900 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature

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Rethinking risk for pneumococcal disease in adults: the role of risk stacking.

Pelton Stephen I SI   Shea Kimberly M KM   Weycker Derek D   Farkouh Raymond A RA   Strutton David R DR   Edelsberg John J  

Open forum infectious diseases 20150101 1


Using data from 3 private healthcare claims repositories, we evaluated the incidence of pneumococcal disease among adults with US Advisory Committee on Immunization Practices (ACIP) defined at-risk conditions or rheumatoid arthritis, lupus, Crohn's disease, and neuromuscular disorder/seizures and those with traditional high-risk conditions. We observed that adults with ≥2 concurrent comorbid conditions had pneumococcal disease incidence rates that were as high as or higher than rates observed in  ...[more]

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