Relationship between serum uric Acid and bone mineral density in the general population and in rats with experimental hyperuricemia.

ABSTRACT:

Unlabelled

Higher serum uric acid concentrations have been associated with higher bone mineral density (BMD) in observational studies of older men and perimenopausal or postmenopausal women, prompting speculation of a potential protective effect of uric acid on bone. Whether this relationship is present in the general population has not been examined and there is no data to support causality. We conducted a cross-sectional analysis of a probability sample of the U.S.

Population

Demographic data, dietary intake, lifestyle risk factors and physical activity assessment data, serum biochemistry including serum uric acid, and BMD were obtained from 6759 National Health and Nutrition Examination Survey (NHANES; 2005-2010) participants over 30 years of age. In unadjusted analyses,

SUBMITTER: Zhang D 

PROVIDER: S-EPMC4439277 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature