Clinico-pathological association of Henoch-Schoenlein purpura nephritis and IgA nephropathy in children.

ABSTRACT:

Objective

Henoch-Schonlein purpura nephritis (HSPN) and IgA nephropathy (IgAN) are similar syndromes. We aimed to determine whether the crescent formation/immunocomplex in glomeruli is associated with the differences of the biochemical indexes between HSPN and IgAN.

Methods

We investigated the medical records of 137 HSPN cases and 41 IgAN cases from January 2009 to April 2014 in Nanjing Children's Hospital of Nanjing Medical University. The clinical and pathological data were analyzed and compared between HSPN and IgAN.

Results

HSPN patients had markedly higher levels of blood white blood cell (WBC), hemoglobulin (Hb) and platelet (PLT), lower levels of hematuria, blood nitrogen (BUN) and C4 compared with IgAN cases. Crescents formation and C3 deposition in the kidney

SUBMITTER: Mao S 

PROVIDER: S-EPMC4440049 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature