Interleukin-8 for diagnosis of neonatal sepsis: a meta-analysis.

ABSTRACT:

Background

Neonatal sepsis (NS) is a life-threatening disorder and an important cause of morbidity and mortality in neonates. Previous studies showed that interleukin 8 (IL-8) may effectively and rapidly diagnose NS.

Objective

We conducted the systematic review and meta-analysis to investigate the diagnostic value of the IL-8 in NS.

Methods

The literature was searched in PUBMED, EMBASE, Cochrane Library, CNKI, VIP and other Chinese Medical Databases during October 1998 to January 2014 using set search criteria. Each included study was evaluated by quality assessment of diagnostic accuracy studies tool. Two investigators independently extracted the data and study characteristics, and disagreements, if any, were resolved by consensus. Meta-disc software was used to calc

SUBMITTER: Zhou M 

PROVIDER: S-EPMC4440704 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature