Outcome discrepancies and selective reporting: impacting the leading journals?

ABSTRACT:

Background

Selective outcome reporting of either interesting or positive research findings is problematic, running the risk of poorly-informed treatment decisions. We aimed to assess the extent of outcome and other discrepancies and possible selective reporting between registry entries and published reports among leading medical journals.

Methods

Randomized controlled trials published over a 6-month period from July to December 31st, 2013, were identified in five high impact medical journals: The Lancet, British Medical Journal, New England Journal of Medicine, Annals of Internal Medicine and Journal of American Medical Association were obtained. Discrepancies between published studies and registry entries were identified and related to factors including registration timing,

SUBMITTER: Fleming PS 

PROVIDER: S-EPMC4440809 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature