Suitability of UK Biobank Retinal Images for Automatic Analysis of Morphometric Properties of the Vasculature.

ABSTRACT:

Purpose

To assess the suitability of retinal images held in the UK Biobank--the largest retinal data repository in a prospective population-based cohort--for computer assisted vascular morphometry, generating measures that are commonly investigated as candidate biomarkers of systemic disease.

Methods

Non-mydriatic fundus images from both eyes of 2,690 participants--people with a self-reported history of myocardial infarction (n=1,345) and a matched control group (n=1,345)--were analysed using VAMPIRE software. These images were drawn from those of 68,554 UK Biobank participants who underwent retinal imaging at recruitment. Four operators were trained in the use of the software to measure retinal vascular tortuosity and bifurcation geometry.

Results

Total operator time

SUBMITTER: MacGillivray TJ 

PROVIDER: S-EPMC4441470 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature