Tiling among stereotyped dendritic branches in an identified Drosophila motoneuron.

ABSTRACT: Different types of neurons can be distinguished by the specific targeting locations and branching patterns of their dendrites, which form the blueprint for wiring the brain. Unraveling which specific signals control different aspects of dendritic architecture, such as branching and elongation, pruning and cessation of growth, territory formation, tiling, and self-avoidance requires a quantitative comparison in control and genetically manipulated neurons. The highly conserved shapes of individually identified Drosophila neurons make them well suited for the analysis of dendritic architecture principles. However, to date it remains unclear how tightly dendritic architecture principles of identified central neurons are regulated. This study uses quantitative reconstructions of dendritic archi

SUBMITTER: Vonhoff F 

PROVIDER: S-EPMC4441823 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature