Retinal nerve fibre layer thickness floor and corresponding functional loss in glaucoma.

ABSTRACT:

Aim

To estimate the floor of retinal nerve fibre layer (RNFL) thickness measurements and the corresponding retinal sensitivity loss in glaucoma.

Methods

Visual field (VF), Spectralis RNFL (83 patients and 37 healthy subjects) and RTVue RNFL data obtained separately (56 patients and 36 healthy subjects) were reviewed. Global and quadrant residual layer thicknesses and corresponding VF losses were estimated using two Bayesian change point models.

Results

The respective residual thicknesses from change point model 1 (CPM1) on Spectralis and RTVue (respectively) were 49.9 and 70.6 µm globally, 57.1 and 83.7 µm superiorly, 55.2 and 79.0 µm inferiorly, 43.1 and 60.5 µm nasally, and 40.1 and 59.5 µm temporally. Corresponding VF losses ranged between -25.1 and -21.7 dB (Spect

SUBMITTER: Mwanza JC 

PROVIDER: S-EPMC4441828 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature