ESTIMATING MEAN SURVIVAL TIME: WHEN IS IT POSSIBLE?

ABSTRACT: For right censored survival data, it is well known that the mean survival time can be consistently estimated when the support of the censoring time contains the support of the survival time. In practice, however, this condition can be easily violated because the follow-up of a study is usually within a finite window. In this article we show that the mean survival time is still estimable from a linear model when the support of some covariate(s) with nonzero coefficient(s) is unbounded regardless of the length of follow-up. This implies that the mean survival time can be well estimated when the support of linear predictor is wide in practice. The theoretical finding is further verified for finite samples by simulation studies. Simulations also show that, when both models are correctly specif

SUBMITTER: Ding Y 

PROVIDER: S-EPMC4442028 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature