Left atrial enlargement and stroke recurrence: the Northern Manhattan Stroke Study.

ABSTRACT:

Background and purpose

Although left atrial enlargement (LAE) increases incident stroke risk, the association with recurrent stroke is less clear. Our aim was to determine the association of LAE with recurrent stroke most likely related to embolism (cryptogenic and cardioembolic) and all ischemic stroke recurrences.

Methods

We followed 655 first ischemic stroke patients in the Northern Manhattan Stroke Study for ≤5 years. LA size from 2D echocardiography was categorized as normal LAE (52.7%), mild LAE (31.6%), and moderate-severe LAE (15.7%). We used Cox proportional hazard models to calculate the hazard ratios and 95% confidence intervals for the association of LA size and LAE with recurrent cryptogenic/cardioembolic and total recurrent ischemic stroke.

Results

LA si

SUBMITTER: Yaghi S 

PROVIDER: S-EPMC4442058 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature