Integration of body temperature into the analysis of energy expenditure in the mouse.

ABSTRACT:

Objectives

We quantified the effect of environmental temperature on mouse energy homeostasis and body temperature.

Methods

The effect of environmental temperature (4-33 °C) on body temperature, energy expenditure, physical activity, and food intake in various mice (chow diet, high-fat diet, Brs3 (-/y) , lipodystrophic) was measured using continuous monitoring.

Results

Body temperature depended most on circadian phase and physical activity, but also on environmental temperature. The amounts of energy expenditure due to basal metabolic rate (calculated via a novel method), thermic effect of food, physical activity, and cold-induced thermogenesis were determined as a function of environmental temperature. The measured resting defended body temperature matched that calcul

SUBMITTER: Abreu-Vieira G 

PROVIDER: S-EPMC4443293 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature