The effect of oscillatory mechanical stimulation on osteoblast attachment and proliferation.

ABSTRACT: The aim of this paper is to investigate the effect of the magnitude and duration of oscillatory mechanical stimulation on osteoblast attachment and proliferation as well as the time gap between seeding and applying the stimulation. Cells were exposed to three levels of speed at two different conditions. For the first group, mechanical shear stress was applied after 20 min of cell seeding. For the second group there was no time gap between cell seeding and applying mechanical stimulation. The total area subjected to shear stress was divided into three parts and for each part a comparative study was conducted at defined time points. Our results showed that both shear stress magnitude and the time gap between cell seeding and applying shear stress, are important in further cell proliferation

SUBMITTER: Aryaei A 

PROVIDER: S-EPMC4443475 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature