Effect of anti-vascular endothelial growth factor therapy on choroidal thickness in diabetic macular edema.

ABSTRACT:

Purpose

To determine the effect of anti-vascular endothelial growth factor (VEGF) therapy on choroidal thickness in eyes with diabetic macular edema (DME).

Design

A retrospective, cohort analysis of 59 eyes from 59 patients with DME without prior anti-VEGF therapy.

Methods

Choroidal thickness was measured using semiautomated segmentation of enhanced depth imaging optical coherence tomography images at 0.5-mm intervals from 2.5 mm nasal to 2.5 mm temporal to the fovea. Changes in choroidal thickness with and without anti-VEGF treatment over 6 months were compared. Best-corrected visual acuity and central foveal thickness were analyzed to evaluate the association of choroidal thickness with functional and anatomic outcomes.

Results

Of the 59 eyes with DME, 26 eye

SUBMITTER: Yiu G 

PROVIDER: S-EPMC4443902 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature