Seasonal influenza vaccination for children in Thailand: a cost-effectiveness analysis.

ABSTRACT:

Background

Seasonal influenza is a major cause of mortality worldwide. Routine immunization of children has the potential to reduce this mortality through both direct and indirect protection, but has not been adopted by any low- or middle-income countries. We developed a framework to evaluate the cost-effectiveness of influenza vaccination policies in developing countries and used it to consider annual vaccination of school- and preschool-aged children with either trivalent inactivated influenza vaccine (TIV) or trivalent live-attenuated influenza vaccine (LAIV) in Thailand. We also compared these approaches with a policy of expanding TIV coverage in the elderly.

Methods and findings

We developed an age-structured model to evaluate the cost-effectiveness of eight vaccination

SUBMITTER: Meeyai A 

PROVIDER: S-EPMC4444096 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature