SEGEL: A Web Server for Visualization of Smoking Effects on Human Lung Gene Expression.

ABSTRACT: Cigarette smoking is a major cause of death worldwide resulting in over six million deaths per year. Cigarette smoke contains complex mixtures of chemicals that are harmful to nearly all organs of the human body, especially the lungs. Cigarette smoking is considered the major risk factor for many lung diseases, particularly chronic obstructive pulmonary diseases (COPD) and lung cancer. However, the underlying molecular mechanisms of smoking-induced lung injury associated with these lung diseases still remain largely unknown. Expression microarray techniques have been widely applied to detect the effects of smoking on gene expression in different human cells in the lungs. These projects have provided a lot of useful information for researchers to understand the potential molecular mechanism

SUBMITTER: Xu Y 

PROVIDER: S-EPMC4444269 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature