Impact of Nutrition on Non-Coding RNA Epigenetics in Breast and Gynecological Cancer.

ABSTRACT: Cancer is the second leading cause of death in females. According to the American Cancer Society, there are 327,660 new cases in breast and gynecological cancers estimated in 2014, placing emphasis on the need for cancer prevention and new cancer treatment strategies. One important approach to cancer prevention involves phytochemicals, biologically active compounds derived from plants. A variety of studies on the impact of dietary compounds found in cruciferous vegetables, green tea, and spices like curry and black pepper have revealed epigenetic changes in female cancers. Thus, an important emerging topic comprises epigenetic changes due to the modulation of non-coding RNA levels. Since it has been shown that non-coding RNAs such as microRNAs and long non-coding RNAs are aberrantly expres

SUBMITTER: Krakowsky RH 

PROVIDER: S-EPMC4445322 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature