Cannabinoid abuse and addiction: Clinical and preclinical findings.

ABSTRACT: Cannabinoid abuse disorders represent a widespread public health issue, but there are no approved medications for their treatment. This review describes efforts to understand the mechanisms of cannabinoid abuse and its adverse effects, to identify molecular targets for pharmacotherapy, and to evaluate potential treatments in human volunteers and animal models of cannabinoid reward, withdrawal, and relapse.

SUBMITTER: Panlilio LV 

PROVIDER: S-EPMC4446186 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature