Exposure to fluoride in drinking water and hip fracture risk: a meta-analysis of observational studies.

ABSTRACT:

Background

Many observational studies have shown that exposure to fluoride in drinking water is associated with hip fracture risk. However, the findings are varied or even contradictory. In this work, we performed a meta-analysis to assess the relationship between fluoride exposure and hip fracture risk.

Methods

PubMed and EMBASE databases were searched to identify relevant observational studies from the time of inception until March 2014 without restrictions. Data from the included studies were extracted and analyzed by two authors. Summary relative risks (RRs) with corresponding 95% confidence intervals (CIs) were pooled using random- or fixed-effects models as appropriate. Sensitivity analyses and meta-regression were conducted to explore possible explanations for heterog

SUBMITTER: Yin XH 

PROVIDER: S-EPMC4447426 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature