Mapping the zoonotic niche of Marburg virus disease in Africa.

ABSTRACT:

Background

Marburg virus disease (MVD) describes a viral haemorrhagic fever responsible for a number of outbreaks across eastern and southern Africa. It is a zoonotic disease, with the Egyptian rousette (Rousettus aegyptiacus) identified as a reservoir host. Infection is suspected to result from contact between this reservoir and human populations, with occasional secondary human-to-human transmission.

Methods

Index cases of previous human outbreaks were identified and reports of infection in animals recorded. These data were modelled within a species distribution modelling framework in order to generate a probabilistic surface of zoonotic transmission potential of MVD across sub-Saharan Africa.

Results

Areas suitable for zoonotic transmission of MVD are predicted in

SUBMITTER: Pigott DM 

PROVIDER: S-EPMC4447827 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature