Self-Assembly of a Library of Polyborate Chiral Anions for Asymmetric Catalytic Quinoline Reduction.

ABSTRACT: The 'template' polyborate BOROX catalysts are shown to mediate the asymmetric transfer hydrogenation of 2-quinolines. The rapid and simple generation of a large family of BOROX catalysts with significantly altered asymmetric pockets is described. A transition state model that explains the enantioselectivity is proposed.

SUBMITTER: Desai AA 

PROVIDER: S-EPMC4448761 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature