The effect of poor sleep quality on mood outcome differs between men and women: A longitudinal study of bipolar disorder.

ABSTRACT:

Background

Sleep disturbance is bi-directionally related to mood de-stabilization in bipolar disorder (BD), and sleep quality differs in men and women. We aimed to determine whether perception of poor sleep quality would have a different effect on mood outcome in men versus women.

Methods

We assessed association between sleep quality (Pittsburgh Sleep Quality Index (PSQI)) at study intake and mood outcome over 2 years in subjects from the Prechter Longitudinal Study of Bipolar Disorder (N=216; 29.6% males). The main outcome measure was the severity, variability, and frequency of mood episodes measured by self-report over 2 years of follow-up. Multivariable linear regression models stratified by sex examined the relationship between PSQI with mood outcomes, while age, stressf

SUBMITTER: Saunders EF 

PROVIDER: S-EPMC4448970 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature