Molecular Detection of Genomic Islands Associated With Class 1 and 2 Integron in Haemophilus influenzae Isolated in Iran.

ABSTRACT: BACKGROUND:High levels of multidrug resistance are usually associated with mobile genetic elements that encode specific resistance genes. Integrons are important genetic elements involved in spreading antibiotic multi-resistance. In special cases, large exogenous segments in bacterial genomes form genomic islands, and one of the functions of these genomic islands is antibiotic resistance. Due to geographical heterogeneity in antibiotic resistance pattern, it is mandatory to determine resistance patterns that are region-specific rather than generalized. OBJECTIVES:The objective of this study was to detect class 1 and 2 integrons in clinical isolates of Haemophilus influenzae. PATIENTS AND METHODS:Antibiogram tests were carried out for twenty clinical isolates collected from different patien

SUBMITTER: Boroumand M 

PROVIDER: S-EPMC4449856 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature