Prospective multicenter international surveillance of azole resistance in Aspergillus fumigatus.

ABSTRACT: To investigate azole resistance in clinical Aspergillus isolates, we conducted prospective multicenter international surveillance. A total of 3,788 Aspergillus isolates were screened in 22 centers from 19 countries. Azole-resistant A. fumigatus was more frequently found (3.2% prevalence) than previously acknowledged, causing resistant invasive and noninvasive aspergillosis and severely compromising clinical use of azoles.

SUBMITTER: van der Linden JW 

PROVIDER: S-EPMC4451897 | biostudies-literature |

REPOSITORIES: biostudies-literature