Characterization of reward and effort mechanisms in apathy.

ABSTRACT: Apathy is a common but poorly understood condition with a wide societal impact observed in several brain disorders as well as, to some extent, in the normal population. Hence the need for better characterization of the underlying mechanisms. The processes by which individuals decide to attribute physical effort to obtain rewards might be particularly relevant to relate to apathy traits. Here, we designed two paradigms to assess individual differences in physical effort production and effort-based decision-making and their relation to apathy in healthy people. Apathy scores were measured using a modified version of the Lille Apathy Rating Scale, suitable for use in a non-clinical population. In the first study, apathy scores were correlated with the degree to which stake (reward on offer) a

SUBMITTER: Bonnelle V 

PROVIDER: S-EPMC4451957 | biostudies-literature | 2015 Feb-Jun

REPOSITORIES: biostudies-literature