Lung parenchymal development in premature infants without bronchopulmonary dysplasia.

ABSTRACT:

Rationale

While infants who are born extremely premature and develop bronchopulmonary dysplasia (BPD) have impaired alveolar development and decreased pulmonary diffusion (DLCO), it remains unclear whether infants born less premature and do not develop BPD, healthy premature (HP), have impaired parenchymal development. In addition, there is increasing evidence that pro-angiogenic cells are important for vascular development; however, there is little information on the relationship of pro-angiogenic cells to lung growth and development in infants.

Objective

and Methods Determine among healthy premature (HP) and fullterm (FT) infants, whether DLCO and alveolar volume (VA) are related to gestational age at birth (GA), respiratory support during the neonatal period (mechanical v

SUBMITTER: Assaf SJ 

PROVIDER: S-EPMC4452454 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature