Neural substrates underlying motor skill learning in chronic hemiparetic stroke patients.

ABSTRACT: Motor skill learning is critical in post-stroke motor recovery, but little is known about its underlying neural substrates. Recently, using a new visuomotor skill learning paradigm involving a speed/accuracy trade-off in healthy individuals we identified three subpopulations based on their behavioral trajectories: fitters (in whom improvement in speed or accuracy coincided with deterioration in the other parameter), shifters (in whom speed and/or accuracy improved without degradation of the other parameter), and non-learners. We aimed to identify the neural substrates underlying the first stages of motor skill learning in chronic hemiparetic stroke patients and to determine whether specific neural substrates were recruited in shifters versus fitters. During functional magnetic resonance im

SUBMITTER: Lefebvre S 

PROVIDER: S-EPMC4452897 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature