Genome sequence of the Drosophila melanogaster male-killing Spiroplasma strain MSRO endosymbiont.

ABSTRACT:

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Spiroplasmas are helical and motile members of a cell wall-less eubacterial group called Mollicutes. Although all spiroplasmas are associated with arthropods, they exhibit great diversity with respect to both their modes of transmission and their effects on their hosts; ranging from horizontally transmitted pathogens and commensals to endosymbionts that are transmitted transovarially (i.e., from mother to offspring). Here we provide the first genome sequence, along with proteomic validation, of an endosymbiotic inherited Spiroplasma bacterium, the Spiroplasma poulsonii MSRO strain harbored by Drosophila melanogaster. Comparison of the genome content of S. poulsonii with that of horizontally transmitted spiroplasmas indicates that S. poulsonii has lost many metabolic path

SUBMITTER: Paredes JC 

PROVIDER: S-EPMC4453565 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature