Ontology highlight
ABSTRACT:
SUBMITTER: Gil-Sanz C
PROVIDER: S-EPMC4455040 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Neuron 20150501 4
Using genetic fate-mapping with Cux2-Cre and Cux2-CreERT2 mice we demonstrated that the neocortical ventricular zone (VZ) contains radial glial cells (RGCs) with restricted fate potentials (Franco et al., 2012). Using the same mouse lines, Guo et al. (2013) concluded that the neocortical VZ does not contain lineage-restricted RGCs. We now show that the recombination pattern in Cux2-Cre/CreERT2 mice depends on genetic background and breeding strategies. We provide evidence that Guo et al. likely ...[more]