Glycated Hemoglobin Level and Mortality in a Nondiabetic Population with CKD.

ABSTRACT:

Background and objectives

Glycated hemoglobin (HbA1c) is used to diagnose diabetes mellitus (DM) and guide its management. The association between higher HbA1c and progression to ESRD and mortality has been demonstrated in populations with DM. This study examined the association between HbA1c and these end points in a population with CKD and without DM.

Design, setting, participants, & measurements

In the hospital-based NephroTest cohort study, measured GFR (mGFR) was taken by (51)Cr-EDTA renal clearance and HbA1c in 1165 adults with nondialysis CKD stages 1-5 and without DM between January 2000 and December 2010. The median follow-up was 3.48 years (interquartile range, 1.94-5.82) for the competing events of ESRD and pre-ESRD mortality. Time-fixed and time-dependent Cox mod

SUBMITTER: Trivin C 

PROVIDER: S-EPMC4455212 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature