Lung cancer incidence and survival among HIV-infected and uninfected women and men.

ABSTRACT:

Objectives

To determine the lung cancer incidence and survival time among HIV-infected and uninfected women and men.

Design

Two longitudinal studies of HIV infection in the United States.

Methods

Data from 2549 women in the Women's Interagency HIV Study (WIHS) and 4274 men in the Multicenter AIDS Cohort Study (MACS), all with a history of cigarette smoking, were analyzed. Lung cancer incidence rates and incidence rate ratios were calculated using Poisson regression analyses. Survival time was assessed using Kaplan-Meier and Cox proportional-hazard analyses.

Results

Thirty-seven women and 23 men developed lung cancer (46 HIV-infected and 14 HIV-uninfected) during study follow-up. In multivariable analyses, the factors that were found to be independently associat

SUBMITTER: Hessol NA 

PROVIDER: S-EPMC4457511 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature