A Meta-Analysis of Concurrent Chemoradiotherapy for Advanced Esophageal Cancer.

ABSTRACT:

Background

Concurrent chemoradiotherapy is a standard treatment for local advanced esophageal cancer, but the outcomes are controversial. Our goals were to compare the therapeutic effects of concurrent chemoradiotherapy and radiotherapy alone in local advanced esophageal cancer using meta-analysis.

Methods

MEDLINE, EMBASE and the Cochrane library were searched for studies comparing chemoradiotherapy with radiotherapy alone for advanced esophageal cancer. Only randomized controlled trials were included, and extracted data were analyzed with Review Manager Version 5.2. The pooled relative risks (RR) and their 95% confidence intervals (CI) were calculated for statistical analysis.

Results

Nine studies were included. Of 1,135 cases, 612 received concurrent chemoradiothera

SUBMITTER: Zhu LL 

PROVIDER: S-EPMC4457836 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature