Data set for the proteomics analysis of the endomembrane system from the unicellular Entamoeba histolytica.

ABSTRACT: Entamoeba histolytica is the protozoan parasite agent of amebiasis, an infectious disease of the human intestine and liver. This parasite contact and kills human cells by an active process involving pathogenic factors. Cellular traffic and secretion activities are poorly characterized in E. histolytica. In this work, we took advantage of a wide proteomic analysis to search for principal components of the endomembrane system in E. histolytica. A total of 5683 peptides matching with 1531 proteins (FDR of 1%) were identified which corresponds to roughly 20% of the total amebic proteome. Bioinformatics investigations searching for domain homologies (Smart and InterProScan programs) and functional descriptions (KEGG and GO terms) allowed this data to be organized into distinct categories. This

SUBMITTER: Perdomo D 

PROVIDER: S-EPMC4459567 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature