Genome-wide expression patterns of calcium-dependent protein kinases in Toxoplasma gondii.

ABSTRACT:

Background

Calcium-dependent protein kinases (CDPKs) are found in plants and some Apicomplexan parasites but not in animals or fungi. CDPKs have been shown to play important roles in various calcium-signaling pathways such as host cell invasion, egress and protein secretion in Toxoplasma gondii. The objectives of the present study were to examine the T. gondii CDPK genes expression patterns during different development stages and stress responses.

Methods

We carried out a comprehensive expression analysis of CDPK genes based on previously published microarray datasets, and we also used real time quantitative RT-PCR to study ten T. gondii CDPK genes expression patterns under acid, alkali, high temperature and low temperature conditions.

Results

Microarrays analysis ind

SUBMITTER: Wang JL 

PROVIDER: S-EPMC4459671 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature