The Efficacy and Clinical Safety of Various Analgesic Combinations for Post-Operative Pain after Third Molar Surgery: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objectives

To run a systematic review and meta-analysis of randomized clinical trials aiming to answer the clinical question "which analgesic combination and dosage is potentially the most effective and safe for acute post-operative pain control after third molar surgery?".

Materials and methods

A systematic search of computer databases and journals was performed. The search and the evaluations of articles were performed by 2 independent reviewers in 3 rounds. Randomized clinical trials related to analgesic combinations for acute post-operative pain control after lower third molar surgery that matched the selection criteria were evaluated to enter in the final review.

Results

Fourteen studies with 3521 subjects, with 10 groups (17 dosages) of analgesic combinations we

SUBMITTER: Au AH 

PROVIDER: S-EPMC4459961 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature