Diversity of the Epsilonproteobacteria Dsb (disulfide bond) systems.

ABSTRACT: The bacterial proteins of the Dsb family-important components of the post-translational protein modification system-catalyze the formation of disulfide bridges, a process that is crucial for protein structure stabilization and activity. Dsb systems play an essential role in the assembly of many virulence factors. Recent rapid advances in global analysis of bacteria have thrown light on the enormous diversity among bacterial Dsb systems. While the Escherichia coli disulfide bond-forming system is quite well understood, the mechanisms of action of Dsb systems in other bacteria, including members of class Epsilonproteobacteria that contain pathogenic and non-pathogenic bacteria colonizing extremely diverse ecological niches, are poorly characterized. Here we present a review of current knowle

SUBMITTER: Bocian-Ostrzycka KM 

PROVIDER: S-EPMC4460558 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature