Cobalt(III)-Catalyzed C-H Bond Amidation with Isocyanates.

ABSTRACT: The first examples of cobalt(III)-catalyzed C-H bond addition to isocyanates are described, providing a convergent strategy for arene and heteroarene amidation. Using a robust air- and moisture-stable catalyst, this transformation demonstrates a broad isocyanate scope and good functional-group compatibility and has been performed on gram scale.

SUBMITTER: Hummel JR 

PROVIDER: S-EPMC4460580 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature