Treatment outcomes in the Tube Versus Trabeculectomy (TVT) study after five years of follow-up.

ABSTRACT:

Purpose

To report 5-year treatment outcomes in the Tube Versus Trabeculectomy (TVT) Study.

Design

Multicenter randomized clinical trial.

Methods

Settings

Seventeen clinical centers.

Study population

Patients 18 to 85 years of age who had previous trabeculectomy and/or cataract extraction with intraocular lens implantation and uncontrolled glaucoma with intraocular pressure (IOP) ≥18 mm Hg and ≤40 mm Hg on maximum tolerated medical therapy.

Interventions

Tube shunt (350-mm(2) Baerveldt glaucoma implant) or trabeculectomy with mitomycin C ([MMC]; 0.4 mg/mL for 4 minutes).

Main outcome measures

IOP, visual acuity, use of supplemental medical therapy, and failure (IOP >21 mm Hg or not reduced by 20%, IOP ≤5 mm Hg, reoperation for glaucoma, or

SUBMITTER: Gedde SJ 

PROVIDER: S-EPMC4460598 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature