Hypothesis: Cryptosporidium genetic diversity mirrors national disease notification rate.

ABSTRACT:

Background

Cryptosporidiosis is a gastrointestinal disease affecting many people worldwide. Disease incidence is often unknown and surveillance of human cryptosporidiosis is installed in only a handful of developed countries. A genetic marker that mirrors disease incidence is potentially a powerful tool for monitoring the two primary human infected species of Cryptosporidium.

Methods

We used the molecular epidemiological database with Cryptosporidium isolates from ZoopNet, which currently contains more than 1400 records with their sampling nations, and the names of the host species from which the isolates were obtained. Based on 296 C. hominis and 195 C. parvum GP60 sequences from human origin, the genetic diversities of Cryptosporidium was estimated for several nations. Not

SUBMITTER: Takumi K 

PROVIDER: S-EPMC4460647 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature