Expansion of the HSFY gene family in pig lineages : HSFY expansion in suids.

ABSTRACT:

Background

Amplified gene families on sex chromosomes can harbour genes with important biological functions, especially relating to fertility. The Y-linked heat shock transcription factor (HSFY) family has become amplified on the Y chromosome of the domestic pig (Sus scrofa), in an apparently independent event to an HSFY expansion on the Y chromosome of cattle (Bos taurus). Although the biological functions of HSFY genes are poorly understood, they appear to be involved in gametogenesis in a number of mammalian species, and, in cattle, HSFY gene copy number may correlate with levels of fertility.

Results

We have investigated the HSFY family in domestic pig, and other suid species including warthog, bushpig, babirusa and peccaries. The domestic pig contains at least two ampli

SUBMITTER: Skinner BM 

PROVIDER: S-EPMC4460688 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature