Functional networks and structural connectivity of visuospatial and visuoperceptual working memory.

ABSTRACT: Neural correlates of working memory (WM) in healthy subjects have been extensively investigated using functional MRI (fMRI). However it still remains unclear how cortical areas forming part of functional WM networks are also connected by white matter fiber bundles, and whether DTI measures, used as indices of microstructural properties and directionality of these connections, can predict individual differences in task performance. fMRI data were obtained from 23 healthy young subjects while performing one visuospatial (square location) and one visuoperceptual (face identification) 2-back task. Diffusion tensor imaging (DTI) data were also acquired. We used independent component analysis (ICA) of fMRI data to identify the main functional networks involved in WM tasks. Voxel-wise DTI analyse

SUBMITTER: Sala-Llonch R 

PROVIDER: S-EPMC4463024 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature