Ultrasound assessment of carotid plaque echogenicity response to statin therapy: a systematic review and meta-analysis.

ABSTRACT:

Objective

To evaluate in a systematic review and meta-analysis model the effect of statin therapy on carotid plaque echogenicity assessed by ultrasound.

Methods

We have systematically searched electronic databases (PubMed, MEDLINE, EMBASE and Cochrane Center Register) up to April, 2015, for studies evaluating the effect of statins on plaque echogenicity. Two researchers independently determined the eligibility of studies evaluating the effect of statin therapy on carotid plaque echogenicity that used ultrasound and grey scale median (GSM) or integrated back scatter (IBS).

Results

Nine out of 580 identified studies including 566 patients' carotid artery data were meta-analyzed for a mean follow up of 7.2 months. A consistent increase in the echogenicity of carotid arte

SUBMITTER: Ibrahimi P 

PROVIDER: S-EPMC4463673 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature