Harms associated with single unit perioperative transfusion: retrospective population based analysis.

ABSTRACT:

Objective

To determine whether perioperative transfusion of as little as one unit of packed red blood cells in the operating room or the day after surgery is associated with measurably increased odds for perioperative ischemic stroke and myocardial infarction.

Design

Retrospective cohort study of hospital administrative data.

Setting

346 hospitals in the United States participating in the claims based Premier Perspective database from 1 January 2009 to 31 March 2012.

Participants

1,583,819 adults who underwent non-cardiac, non-intracranial, non-vascular surgery and required a stay of at least one night in hospital and did not receive packed red blood cells on days two to seven after surgery.

Intervention

Transfusion of packed red blood cells on the day o

SUBMITTER: Whitlock EL 

PROVIDER: S-EPMC4463965 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature