The histone methyltransferase SDG8 mediates the epigenetic modification of light and carbon responsive genes in plants.

ABSTRACT:

Background

Histone methylation modifies the epigenetic state of target genes to regulate gene expression in the context of developmental and environmental changes. Previously, we used a positive genetic screen to identify an Arabidopsis mutant, cli186, which was impaired in carbon and light signaling. Here, we report a deletion of the Arabidopsis histone methyltransferase SDG8 in this mutant (renamed sdg8-5), which provides a unique opportunity to study the global function of a specific histone methyltransferase within a multicellular organism.

Results

To assess the specific role of SDG8, we examine how the global histone methylation patterns and transcriptome were altered in the sdg8-5 deletion mutant compared to wild type, within the context of transient light and carbon t

SUBMITTER: Li Y 

PROVIDER: S-EPMC4464704 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature