Time from convulsive status epilepticus onset to anticonvulsant administration in children.

ABSTRACT:

Objective

To describe the time elapsed from onset of pediatric convulsive status epilepticus (SE) to administration of antiepileptic drug (AED).

Methods

This was a prospective observational cohort study performed from June 2011 to June 2013. Pediatric patients (1 month-21 years) with convulsive SE were enrolled. In order to study timing of AED administration during all stages of SE, we restricted our study population to patients who failed 2 or more AED classes or needed continuous infusions to terminate convulsive SE.

Results

We enrolled 81 patients (44 male) with a median age of 3.6 years. The first, second, and third AED doses were administered at a median (p25-p75) time of 28 (6-67) minutes, 40 (20-85) minutes, and 59 (30-120) minutes after SE onset. Considering A

SUBMITTER: Sanchez Fernandez I 

PROVIDER: S-EPMC4464741 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature