Multi-component molecular-level body composition reference methods: evolving concepts and future directions.

ABSTRACT: Excess adiposity is the main phenotypic feature that defines human obesity and that plays a pathophysiological role in most chronic diseases. Measuring the amount of fat mass present is thus a central aspect of studying obesity at the individual and population levels. Nevertheless, a consensus is lacking among investigators on a single accepted 'reference' approach for quantifying fat mass in vivo. While the research community generally relies on the multi-component body volume class of 'reference' models for quantifying fat mass, no definable guide discerns among different applied equations for partitioning the four (fat, water, protein and mineral mass) or more quantified components, standardizes 'adjustment' or measurement system approaches for model-required labelled water dilution vol

SUBMITTER: Heymsfield SB 

PROVIDER: S-EPMC4464774 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature