Associations between sex and incident chronic kidney disease in a prospective diabetic cohort.

ABSTRACT:

Aim

Women with diabetes have a higher prevalence of chronic kidney disease (CKD) risk factors compared with men, but whether they are at higher risk for incident CKD remains uncertain.

Methods

This was a prospective, observational cohort study of 1464 patients with diabetes and normal renal function, recruited from primary care clinics at a vertically integrated healthcare system in Seattle, WA, USA. The primary predictor was sex. Incident CKD was defined by an estimated glomerular filtration rate (eGFR) <60 mL/min per 1.73 m(2) by Chronic Kidney Disease-Epidemiology equations or sex-specific microalbuminuria (urine albumin/creatinine ratio ≥25 mg/g for women or ≥17 mg/g for men).

Results

Of the 1464 patients (52.0% women), CKD incidence rates were 154.0 and 144.3 cas

SUBMITTER: Yu MK 

PROVIDER: S-EPMC4465880 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature