Quality of life and symptom assessment in randomized clinical trials of bladder cancer: A systematic review.

ABSTRACT:

Objectives

Patient-reported outcomes (PRO) help patients, caretakers, clinicians, and policy makers make informed decisions regarding treatment effectiveness. Our objective was to assess the quality of PRO reporting and methodological strengths and weaknesses in randomized controlled trials (RCT) in bladder cancer.

Methods

A systematic literature search of bladder cancer RCT published between January 2004 and March 2014 was performed. Relevant studies were evaluated using a predetermined extraction form that included trial demographics, clinical and PRO characteristics, and standards of PRO reporting based on recommendations of the International Society for Quality of Life Research.

Results

In total, 9 RCTs enrolling 1,237 patients were evaluated. All studies were in

SUBMITTER: Feuerstein MA 

PROVIDER: S-EPMC4466160 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature