Micro- and Nanosized Particles in Nasal Mucosa: A Pilot Study.

ABSTRACT:

Objective

The aim of this prospective study is to evaluate presence and quantity of micro- and nanosized particles (NPs) and interindividual differences in their distribution and composition in nasal mucosa.

Methods

Six samples of nasal mucosa obtained by mucotomy from patients with chronic hypertrophic rhinosinusitis were examined. Samples divided into 4 parts according to the distance from the nostrils were analyzed by scanning electron microscopy and Raman microspectroscopy to detect solid particles and characterize their morphology and composition. A novel method of quantification of the particles was designed and used to evaluate interindividual differences in distribution of the particles. The findings were compared with patients' employment history.

Results

In

SUBMITTER: Cabalova L 

PROVIDER: S-EPMC4466340 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature