The role of FDG-PET in defining prognosis of Hodgkin lymphoma for early-stage disease.

ABSTRACT: Given the excellent survival rates for early-stage Hodgkin lymphoma (HL), the young age of many patients, and concerns regarding acute and late treatment-related toxicities, there is a desire to have a predictive tool that enables therapy to be tailored toward the individual patient. Early (or interim) (18)F-fluorodeoxyglucose positron emission tomography with computerized tomography (FDG-PET/CT), as a test of tumor sensitivity to ongoing/planned therapy, has been shown to be prognostic for survival in HL. Based on results of interim FDG-PET/CT, therapy may be subsequently modified through minimization or via intensification for low- and high-risk patient populations, respectively (ie, response-adapted therapy). Important data have been generated to standardize the interpretability and rep

SUBMITTER: Evens AM 

PROVIDER: S-EPMC4467863 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature