Rectal bleeding after radiation therapy for endometrial cancer.

ABSTRACT:

Background and purpose

The goals of this study were to determine the rate and risk factors of rectal bleeding (RB) after external beam radiotherapy and vaginal brachytherapy (EBRT +VB), and to compare these data to previously unreported RB rates from PORTEC-2 patients receiving EBRT or VB alone.

Materials and methods

Retrospective chart review identified 212 endometrial cancer patients receiving adjuvant EBRT+VB between 2006 and 2013. Patient-reported RB data were also obtained from PORTEC-2 patients randomized to EBRT (n=166) or VB (n=182). The two populations were compared using an RB scale of symptom severity.

Results

After a median 35months, 17.9% of EBRT+VB patients (n=38) experienced any RB with 1.9% (n=4) having bleeding requiring intervention. Age ⩽70years was

SUBMITTER: Mitra D 

PROVIDER: S-EPMC4467995 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature